Isolation and characterization of Caulobacter crescentus flagellar hooks

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Isolation and characterization of NaCl-sensitive mutants of Caulobacter crescentus.

An attempt to characterize Caulobacter crescentus genes important for the response to high concentrations of NaCl was initiated by the isolation of mutants defective in survival in the presence of 85 mM NaCl. A transposon Tn5 library was screened, and five strains which contained different genes disrupted by the transposon were isolated. Three of the mutants had the Tn5 in genes involved in lip...

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Reconstitution and purification of flagellar filaments from Caulobacter crescentus.

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PflI, a protein involved in flagellar positioning in Caulobacter crescentus.

The bacterial flagellum is important for motility and adaptation to environmental niches. The sequence of events required for the synthesis of the flagellar apparatus has been extensively studied, yet the events that dictate where the flagellum is placed at the onset of flagellar biosynthesis remain largely unknown. We addressed this question for alphaproteobacteria by using the polarly flagell...

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Physical characterization of Caulobacter crescentus flagella.

Preparations of intact flagella isolated from Caulobacter crescentus CB13B1a were found to contain two protein species of apparent molecular weights 28,000 and 25,000. Both proteins cross-reacted completely with each other and with purified flagella in Ouchterlony double-immunodiffusion assays. The amino acid compositions of the isolated proteins were similar to one another but precluded any pr...

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Isolation of spontaneously derived mutants of Caulobacter crescentus.

Caulobacter crescentus has a penicillinase which precludes the use of penicillin for mutant enrichment. However, two other antibiotics, fosfomycin and D-cycloserine, can be enrich for C. crescentus mutants. In enrichment procedures for C. crescentus auxotrophs, spontaneously derived mutants occur at a frequency of 5-10% among the survivors of an enrichment procedure. Consequently, large numbers...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 1978

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.136.2.795-798.1978